About the GoSilico company
GoSilico digitalizes biopharmaceutical downstream process development with computer simulation. Biopharmaceutical companies, CDMOs and vendors all over the globe rely on our unique simulation-based development approach.
It is our mission to accelerate downstream process development with computer simulation. Our revolutionary DSPX simulation technology paves the way towards digitalized downstream process development, enabling higher cost efficiency, reduced time-to-market, increased process understanding, and complete knowledge management – all in line with growing regulatory demands on Quality-by-Design.
The future of biopharmaceutical process development is driven by in silico solutions. It is only a matter of time until downstream process development and regulatory approval in life sciences will be compelled to involve computer simulation. We provide the tools to master this digital transition.
Founded in 2016, GoSilico now serves more than half of the world’s top 10 leading biopharmaceutical companies. Numerous vendors and CDMOs digitalize their industrial downstream development using our simulation approach to provide a mechanistic insight into their products and processes.
GoSilico was founded by Teresa Baumann, Tobias Hahn, Thiemo Huuk and Jürgen Hubbuch in 2016 as a spin-off of Karlsruhe Institute of Technology (KIT). From 2011 to 2015, our ChromX chromatography simulation software was developed during the PhD of the co-founders in close collaboration with large biopharmaceutical companies such as Roche Diagnostics GmbH. At that time, ChromX was primarily intended as an academic research tool, but industrial interest quickly grew. Once they had finished their PhDs, the founders established GoSilico in Karlsruhe, Germany. To meet the overwhelming interest of the biopharmaceutical industry, the founders quickly assembled a world-class team of experts. GoSilico and its simulation technology soon became the benchmark for downstream process simulations in the biopharmaceutical industry. Furthermore, an academic version of ChromX is being used in more than 40 countries, enabling academic researchers and students all over the globe to simulate liquid chromatography on the computer and to educate the workforce of the future.
Based on five years of experience providing the industry with a world-leading chromatography simulation software ChromX, we realized that the industry needs more: a holistic downstream processing suite that spans the entire downstream process chain. GoSilico therefore developed and designed DSPX as a comprehensive simulation suite, ready to simulate all the key unit operations within the downstream process environment. DSPX is designed as a modular system, where each unit operation is treated as an independent unit. All unit operations can easily be combined and plugged together. Individual process steps can be treated independently or even optimized together. DSPX facilitates a holistic digital process view that previously never existed.
GoSilico’s founders – the pioneers of in silico process development
Our work demonstrates that the future of biopharmaceutical process development will be driven by in silico solutions. It is not only our profession but also our passion to enable the digital transformation of process development.
developed the prototype of the ChromX software during his PhD in Bioengineering. In this, he greatly benefitted from his experience in software development, which he had gained during his previous studies in applied mathematics. Tobias supervises the product development and service offers at GoSilico.
studied biotechnology, followed by an industry-oriented PhD in Bioengineering. In his PhD, he applied ChromX in a collaboration project with Roche Diagnostics and gained extensive expertise in industrial downstream process development. Given his profound background in biotechnology, Thiemo is responsible for the acquisition of new customers.
holds a Diplom in Meteorology and a PhD in applied mathematics. Teresa is responsible for GoSilico’s compliance with the highest quality standards. With her profound simulation background, she also leads the marketing activities at GoSilico.
Prof. Jürgen Hubbuch
is a professor of biopharmaceutical process engineering at KIT. With his creative and visionary mindset, he develops new technologies at his institute but also accompanies innovation processes in pharmaceutical companies. At GoSilico, Jürgen provides his industrial insight, expertise and vision as a scientific advisor.
With our unique experience in implementing simulation tools in the biopharmaceutical industry, experience in leading many successful projects and a strong scientific background, we are your partner for digitalizing your downstream process development. We are committed to your success and offer you support wherever we can. Our activities are driven by our core values:
- Passion for game-changing solutions to foster sustainable innovation.
- Profound expertise and professionalism leading all our actions.
- Reliable partnerships on our joint route towards the goal.
- Respect, trust and responsibility guiding our daily work.
We are committed to providing simulation software of the highest quality and accuracy as well as effective services and an outstanding customer service. Our product and services are designed to be compliant with all relevant industry-specific expectations and standards.
We strive to continuously improve our product and services, our business processes and our organization with respect to our customers’ requirements and regulations. Since 2018, GoSilico has been ISO 9001:2015 certified in quality management as part of our intrinsic commitment to long-lasting success. We guarantee the highest quality expectations at all times – so we can become and stay one of your trusted partners.