From April 2nd until April 7th, Thiemo and Teresa presented GoSilico at the Annual Spring Meeting of the American Chemical Society in San Francisco, USA, and highlighted the capabilities of GoSilico’s simulation software ChromX for an in silico process development.
On Monday morning, Teresa gave a presentation about the “Next Generation Bioprocessing. Stop Experimenting. GoSilico.” In the framework of a start-up session, she presented the perspectives and prospects of a computer-guided process development for the development of downstream purification processes. Following a quick technology introduction into GoSilico’s chromatography simulation software ChromX, she showcased its capabilities for process development by means of several case-studies. Amongst others, she showed how to simulate a crude feedstock and optimize the process, as well as using computer models to compare a batch vs. a continuous processing system. After the talk, she was given the honour to contribute to a panel discussion about financing and fundraising of biotech start-ups.
Later the week, Thiemo presented a poster on a very recent case study, where the combination of a platform process and a Design-of-Experiments approach had failed in finding a suitable purification process for a monoclonal antibody, better than 70% yield. Using our simulation software ChromX, we could find a process with more than 95% yield. Interested, how this was possible? See the poster.
ACS was a great opportunity to meet both industry and academia. We both enjoyed the interesting discussions following the talks and during the poster session.