GoSilico offers trainings on in-silico simulation of liquid chromatography. Our trainings intent to introduce your team to model-based process development and to acquaint you with state-of-the-art methods and technologies. Trainings take place regularily throughout the year in Karlsruhe, Germany. In-house trainings at your company are also possible. For more details send us your request and we will propose a tailored training program. Our team of mathematicians, software engineers, chemical engineers and biotechnologists is looking forward to sharing its knowledge and experience in in-silico chromatography with you.
Subjects Taught In Our Courses
Insight into mathematical modeling of chromatography. Which phenomena are accounted for and how do they affect the chromatogram?
How can system- and component-specific model-parameters be determined experimentally? How can information from offline analytics be included?
Objectives such as yield and purity might compete with each other. Multi-criteria optimization allows to choose the best fitting compromise in retrospect.
Experiments can be optimally planned for model calibration, such that the highest statistical quality is achieved with a minimal number of experiments.
How can model quality be assessed and how do uncertainties in model parameters lead to uncertainties in the process quality attributes?
Simulating and visualizing intra-column processes and drawing conclusions about process performance: resin utilization, displacement effects, etc.